The Greatest Loss in Samsara

If one can learn Buddhism to the point of becoming simple-minded, like a fool who disregards personal interests, then the state of non-self is achieved, signifying accomplishment. When one is unaware of the existence of "I," unaware of others deceiving, scolding, humiliating, or belittling oneself, remaining unmoved by others' words and making no calculations—as if these matters were unrelated to oneself—then the supreme fruit of non-self will be attained. People fear being overly shrewd, not foolish in the slightest, constantly scheming, pursuing advantage and avoiding harm, acting selfishly and self-interestedly. Those who cling to the notion of "I" are never foolish; they are always calculating, unwilling to suffer losses. Yet, in the end, they are ensnared by karma, suffering the loss of the cycle of birth and death. Dwelling within the six realms, they suffer greatly, failing to attain any supreme fruit. How could they not suffer loss?